We are a basic and translational oncology laboratory with a mission to improve the diagnosis and treatment of pancreatic cancer. We use genomics, functional genetic screening, molecular and cell biology approaches to:
Understand the genetics and biology of pancreatic cancer and other RAS-driven cancers
Discover and mechanistically define new therapeutic strategies that can be validated in preclinical cancer models
Translate laboratory findings into new clinical trials
Our research team is comprised of bench scientists, computational biologists and clinicians who work together with a common goal to improve the care of pancreatic cancer patients.
Aguirre Lab News
2022-02-23 Congratulations and best of luck to Shengwu for starting a new position at Theseus Pharmaceuticals!
2021-07-14 Best of luck to our former postdoctoral researcher Jasper with his new pharmaceutical startup Promakhos Therapeutics!
2021-04-26 Congratulations to Kristen for joining UMass Medical School's Class of 2025!
2021-04-10 Dr. Aguirre was named an AACR NextGen Star and presented on the lab's recent research in genetics at the NextGen Stars Spotlight Session. Click here to read more!
2020-10-27 Dr. Aguirre was recently interviewed and featured in an article by Let's Win! Pancreatic Cancer investigating the relationship between tumor subtypes and prognosis. Click here to read more!
Check out the Aguirre Lab's feature in "An Army of Investigators" and in "Pancreatic Cancer Survivors Series- Year Three" from Let's Win! Pancreatic Cancer below!